目的 《中国药典》收载的天南星基源包括天南星科植物天南星、异叶天南星、东北天南星，于我国辽宁、云南省、四川分布最为广泛。天南星化学成分复杂，但其主要起药理药效活性的化学成分报道并不完善；且无法识别不同来源天南星之间的区别。且目前用于正伪品鉴定与质量控制的天南星专属HPLC指纹图谱相关研究较少，故本文从脂类成分入手，通过分离纯化脂类成分，有助于天南星专属HPLC指纹图谱的建立，为不同基源天南星药材与饮片品质的鉴别提供依据。方法 本方法采用从天南星块茎中提取分离化合物的完整流程：首先将药材切片后用95%乙醇进行回流提取，浓缩后得总浸膏；接着通过硅胶柱层析进行粗分，采用不同比例的二氯甲烷-甲醇和乙酸乙酯-甲醇系统进行梯度洗脱，通过薄层色谱监测并合并相似流分，获得11个组分；取组分Ⅲ经Sephadex LH-20凝胶柱层析，以70%甲醇洗脱，通过聚酰胺薄层监测合并得到4个亚组分；最后经液相分析后，将目标组分通过半制备液相色谱进行最终纯化，获得较纯样品。结果：分离得到2个单体成分，结合NMR及理化性质，鉴定为松柏醇、(E)-p-Coumaryl Alcohol。结论：松柏醇、(E)-p-Coumaryl Alcohol在天南星中首次分离得到，提示天南星中脂溶性成分中苯丙素类成分可能含量较高。

Objective The basic sources of A.erubescens in “Pharmacopoeia of the People's Republic of China” include Arisaema erubescens(wall.) Schott. Arisaema.heterophyllum Blume and Arisaema.amurense Maxim, which is most widely distributed in Liaoning, Sichuan and Yunnan provinces of China.The chemical constituents of A.erubescens are complex, but the reports of its main pharmacological and pharmacodynamic chemical constituents are not perfect; And it is impossible to identify the difference between A.erubescens from different sources. At present, there are few studies on the exclusive HPLC fingerprint of A.erubescens for identification and control of genuine and counterfeit products. Therefore, the separation and purification of lipid components in this paper is helpful to establish the exclusive HPLC fingerprint of A.erubescens and provide a basis for the identification of the quality of different basic A.erubescens and its decoction pieces. Methods:This method describes a complete process for the extraction and isolation of compounds from the tubers of *Arisaema heterophyllum*. First, the sliced medicinal material was subjected to reflux extraction with 95% ethanol, followed by concentration to obtain a total extract. The extract was then roughly separated by silica gel column chromatography using a gradient elution with dichloromethane-methanol and ethyl acetate-methanol solvent systems in varying ratios. The fractions were monitored by thin-layer chromatography (TLC), and those with similar compositions were combined to yield 11 fractions. Fraction III was further separated by Sephadex LH-20 gel column chromatography with 70% methanol as the eluent. The subfractions were monitored by polyamide TLC and combined to obtain four subfractions. Finally, after analysis by liquid chromatography, the target subfraction was purified using semi-preparative liquid chromatography to obtain a relatively pure sample. Results Two monomers were isolated and identified as terpineol and (E)-p-Coumaryl Alcohol by combining NMR and physicochemical properties. Conclusion:Pine alcohol and (E)-p-Coumaryl Alcohol were isolated from A.erubescens for the first time.It is suggested that the content of phenylpropanoids in fat-soluble components of A.erubescens may be higher.